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The BioEnterprise Initiative consists of companies formed, recruited, and accelerated through the combined efforts of BioEnterprise and its partner institutions' commercialization offices, including the Case Office of Technology Transfer, Cleveland Clinic Innovations, University Hospitals Case Medical Center - Center for Clinical Research and Summa Enterprise Group. The companies have collectively attracted over $1.2 billion in funding since 2002.
Companies > Commercial

Arteriocyte Cellular therapies and equipment

Pathfinder Biotech High-sensitivity flow cytometry platform

NeoProteomics Protein biomarker discovery tools

ChanTest Ion channel-based discovery platform

Ricerca Drug development CRO

OrthoHelix Surgical Designs Instruments and implants for small bones and joints

Proxy Biomedical Implantable meshes and biomaterials for surgical tissue repair

Theken Spinal implants, instruments and osteobiologics

Checkpoint Surgical Intraoperative nerve locator

NDI Medical Peripheral nerve stimulation for various applications

Synapse Biomedical Neurostimulation for respiratory support

Imalux Optical coherence tomography for tissue visualization

Simbionix Interactive medical simulators and simulation software

Superior Products, Inc. Compressed gas products for medical and industrial applications

Syncro Medical Innovations Magnetically-guided feeding tubes

Lexi-Comp Clinical drug informatics databases

Within3 Online communities for life science professionals

Workflow.com EHR for small physician practices

PartsSource Repair and replacement parts for hospital equipment

Rosco Medical Specialty distributor of HME parts and supplies

ARIS Teleradiology Comprehensive teleradiology services

Cornerstone Medical Services DME distribution

SarahCare Adult day care services

Therapy Partners Contracted physical, occupational and speech therapy services

Eris Medical Technologies Revenue integrity software

Human Arc Reimbursement recovery

MediQuant Legacy data management solutions, medical necessity content and software

StreamlineMD EMR solution combining software, local training and support

RIS Logic Radiology information systems (RIS)

American Safety & Health Institute

Whole Health On-site health care industry

HCS Revenue Cycle Management

Nextmed Revenue Cycle Management

COMS Interactive, LLC

IntellisEPM

OnShift Nurse scheduling and communications software for the Long Term Care industry.

Cleveland HeartLab

CoverMyMeds Automated Prior Authorization for Pharmaceuticals

Dapcel, Inc. Gene redesign for recombinant protein production, protein activity assays

PediaCath Pediatric catheters

Polgenix GPCR protein production and crystalization

BioInvision Small animal 3D image

Innovative Medical Equipment, LLC Medical Device Manufacturing , Marketing and Licensing

Ganeden Biotech Probiotics licensing model

NI Medical Noninvasive cardiac ouput monitoring for CHF

SecuReach

ImageIQ Inc. Image Analysis and Visualization Services

iRxReminder Real time mobile data capture for clinical trials.

Life Core Technologies Developed medical device that induces cerebral therapeutic hypothermia

NeuroWave Systems Inc. Innovative brain monitors for Anesthesia, Critical Care & Neurology

ForTec Companies Providing mobile technology, laser fibers & service solutions


Nervomatrix, Ltd. Auto targeting Neurostimulation for pain relief

Refresh Dental Acquires and restructures dental practices

Tradex International Supplier of medical exam and food service grade disposable latex, nitrile and vinyl gloves.

Nuvon Device Interoperability and Connectivity

Cervilenz Screening devices for improved obstetrical outcomes

IceCure Innovative cryotherapy solutions

Medic Vision CT dose reduction

Recent News

»  Checkpoint Surgical Raises $1.7 Million

»  OnShift Raises $3 Million

»  Minnesota, Ohio, Missouri Attract Most Midwest Health Care Investment

»  SPR Therapeutics Raises $2.2 Million

»  Philips Healthcare and Steris Announce Cleveland Expansions




Commercialized Products & Services


Syncro Blue Tube
One of the many health care innovations brought to market by client companies.
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Exit Companies



Since 2002, 21 Cleveland-area health care companies have had successful exits.

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Cleveland Medical Mart & Convention Center



The world’s only convention facility created for the health care industry.
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